HER2 Testing in Invasive Breast Cancer: a Comparison between Immunohistochemistry and FISH Assays
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FISH testing of HER2 immunohistochemistry 1+ invasive breast cancer with unfavorable characteristics
Diagnostic assays for human epidermal growth factor receptor 2 (HER2) expression have a high predictive value because patients with HER2-positive tumors could benefit from HER2-targeted therapy. The aim of the present study is to analyze the incidence of HER2 gene amplification in selected tumors with adverse features that scored 1+ by immunohistochemistry (IHC). For that purpose, 331 consecuti...
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background : in developed or developing countries, the most common cancer in women is breast cancer with a pick in 40–50 years in asia. herein, we compared the association between ihc with fish in her2-positive breast cancer patients and affection of trastuzumab on disease free survival and overall survival (os). subjects and methods: immunohistochemical (ihc) analysis of hormone receptors and ...
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عنوان ژورنال
دوره 8 شماره 3
صفحات 0- 0
تاریخ انتشار 2020-08
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